Video: Telomere Biology Disorders explained

Video: Telomere Biology Disorders explained

Short telomeres and Telomere Biology Disorders explained

Telomere Biology Disorders (TBDs) are also known as Short Telomere Syndromes or telomeropathies. This video explores what causes TBDs and how they can impact people’s health. Telomere Biology Disorders (TBDs) are characterized by genetic deficits affecting telomere maintenance and by the presence of very short telomeres. Symptoms of TBDs can range significantly from person-to-person. In […]

Video: How telomere shortening affects aging

The End Replication problem and how it affects aging

Telomeres, in particular telomere length, have been shown to play a role in aging. In this video we explore how and why telomere shortening affects the aging process. Telomeres are unique structures of proteins and DNA, found on the ends of our chromosomes. Each time cells replicate, the number of DNA repeats making up our […]

Guest blog: The CPFF are honouring those touched by pulmonary fibrosis during Awareness Month

Guest blog from CPFF for PF Awareness Month

This guest blog, from Sharon Lee, Executive Director at CPFF, is to mark Pulmonary Fibrosis Awareness Month this September. Find out what the organization is doing to raise awareness and how you can show your support. Throughout the month of September, the Canadian Pulmonary Fibrosis Foundation (CPFF) is sharing the stories of those living with […]

Guest blog: A Patient’s Guide to Participating in Pulmonary Fibrosis Awareness Month

Pulmonary Fibrosis Awareness Month presented by RepeatDx

Ahead of Pulmonary Fibrosis Awareness Month, which is marked every September, Laura Devitt, Director, Programs at Pulmonary Fibrosis Foundation kindly shared the below information about getting involved. Every September, those who have been impacted by pulmonary fibrosis (PF) unite for Pulmonary Fibrosis Awareness Month (PFAM). Melissa King, a PFF Ambassador from New York, has participated in […]

How do telomeres affect cancer?

How do telomeres affect cancer?

Telomeres shorten as we age and the risk of cancer increases as we get older; here we explore some ways telomeres affect cancer risk. Cancer is a leading cause of death worldwide and with rates of many cancers increasing year on year, it is a priority research area in terms of improving understanding, diagnosis and […]

Telomeres and aging

Telomeres and aging blog

Telomere length is often considered a biological marker for aging and has been linked to cell lifespan, as well as certain diseases. Here we take a closer look at the relationship between telomeres and aging. What is a telomere? A telomere is a repetitive chain of DNA repeats found on the end of our chromosomes. […]

Why do telomeres shorten?

Why do telomeres shorten

Telomeres play an important role in protecting our chromosomes, but as we age, they decrease in length. In this blog we explore how and why telomeres shorten. Telomere structure Human telomeres are made up of thousands of repeats of the same DNA sequence (TTAGGG), bound by a special set of proteins called shelterin. They are […]