Age-associated telomere attrition of lymphocytes in vivo is co-ordinated with changes in telomerase activity, composition of lymphocyte subsets and health conditions. Lin Y, Damjanovic A, Metter EJ, Nguyen H,. et al. Clin Sci (Lond). 2015 Mar 1;128(6):367-77.
Telomere length in inherited bone marrow failure syndromes. Alter BP, Giri N, Savage SA, Rosenberg PS. Haematologica. 2015 Jan;100(1):49-54
Independent Study Finds Flow-fish Technique Superior as Performed by Repeat Diagnostics.
“In the clinical setting, flow-FISH was more accurate, reproducible, sensitive, and specific in the measurement of human leukocyte’s telomere length in comparison to qPCR.” Read more
4th Marrow Failure and Myelodysplasia Patient and Family Conference
Repeat Diagnostics is happy to sponsor this conference held at the Hospital for Sick Children in Toronto on October 26, 2014.
Dubowitz syndrome is a complex comprised of multiple, genetically distinct and phenotypically overlapping disorders. Stewart DR, Pemov A, Johnston JJ, et al. PLoS One. 2014 Jun 3;9(6)
Response to androgen therapy in patients with dyskeratosis congenita. Khincha PP, Wentzensen IM, Giri N, Alter BP, Savage SA. Br J Haematol. 2014 May;165(3):349-57
Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): an initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC). Williams DA, Bennett C, Bertuch A, Bessler M, et al. Pediatr Blood Cancer. 2014 May;61(5):869-74
6-panel TLM Assay Diagnostic Test of Choice in Identifying Ppatients with Dyskeratosis Congenita
Repeat Diagnostics’ 6-Panel telomere assay, is the diagnostic test of choice in identifying patients with Dyskeratosis Congenita (DC), an inherited bone marrow failure syndrome. Physicians from seven institutions including NCI and NIH reported that the QPCR relative measurement lacked sensitivity and would lead to misdiagnosis of 60% of known DC patients. Read more